Microflora of upper parts of gastrointestinal tract during acute necrotizing pancreatitis

  • O. V. Rotar Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
  • I. V. Khomiak Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
  • V. I. Rotar Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
  • A. I. Khomiak Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
  • V. D. Shafraniuk Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
  • O. V. Hrama Higher State Educational Establishment of Ukraine «Bukovinian State Medical University»
Keywords: Acute pancreatitis, bacterial colonization, purulent septic complications

Abstract

Analysis of results of treatment of 153 patients with acute necrotizing pancreatitis has been performed. Small intestinal content at admission, fluid and necrotic collections were gathered for microbiological investigation. At 57,4% of patients 8 strains of gramm negative microorgamisms were identified from small intestine before operation. Similar microflore were cultivated from pathological foci at 57,4% of patients after operation. Minimal inhibitory concentration of rifaximin from < 0,25 till 8 µg/ml and ciprofloxacin from 0,25 till 1 µg/ml suppressed growth of 100% of isolated microorganisms in vitro.

References

Usenko OY, Kopchak VM, Khomiak, IV et al. Resultsofsurgicaltreatmentofparaduodenal(groove) pancreatitis. Klinicheskaia Khirurgiia. 2019; 85 (11): 5–8. DOI: 10.26779/2522-1396.2018.11.05.

Dronov ОІ, Nastashenko ІL, Susak YМ et al. Surgical treatment of patients, suffering an acute biliary pancreatitis and biliary hypertension. Klinicheskaia Khirurgiia. 2018; 85 (4): 5-8. DOI: 10.26779/2522-1396.2018.04.05.

Mutsaers SN. Current Application of Selective Decontamination of the Digestive Tract, Perioperative Antibiotics and Mechanical Bowel Preparation in Surgical Departments in the Netherlands. Dig Surg. 2011; 28 (5–6): 338–344. DOI: 10.1159/000331318.

Banks PA, Bollen TL, Dervenis C et al. Acute Pancreatitis Classification Working Group. Classification of acute pancreatitis – 2012: revision of the Atlanta classification and definitions by international consensus. Gut 2013; 62 (1): 102–111. DOI: 10.1136/gutjnl-2012-302779.

Boyko, VV, Lykhman, VM, Shevchenko OM et al. Tactics of diagnosis and treatment in liquid-cystic growth in pancreatic gland. Klinicheskaia Khirurgiia. 2019; 86 (3): 3–6. DOI: 10.26779/2522-1396.2019.03.03.

Shevchuk IM, Pylypchuk VI, Khrunik AD, Gedzik, SM. Surgical treatment of chronic pancreatitis with biliary hypertension. Klinicheskaia Khirurgiia. 2017; 84 (8): 27–30. DOI: 10.26779/2522-1396.2017.08.27.

Glagolieva AY, Krestianov MY, Lysenko VM et al. Clinical experience of perioperative application of decamethoxin without application of antibiotics. Klinicheskaia Khirurgiia. 2018; 85 (8): 44–48. DOI: 10.26779/2522-1396.2018.08.44.

Published
2019-12-20
How to Cite
Rotar, O. V., Khomiak, I. V., Rotar, V. I., Khomiak, A. I., Shafraniuk, V. D., & Hrama, O. V. (2019). Microflora of upper parts of gastrointestinal tract during acute necrotizing pancreatitis. Modern Medical Technology, (4(43), 62-65. https://doi.org/10.34287/MMT.4(43).2019.11
Section
Original research