Effect of additional strengthening of colonic anastomosis on abdominal contamination severity

  • M. M. Mylytsia State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine"
  • К. M. Mylytsia State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine"
  • V. V. Steblianko State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine"
  • V. V. Soldusova State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine"
  • V. S. Kazakov State institution "Zaporizhia Medical Academy of Post-Graduate Education Ministry of Health of Ukraine"
Keywords: Insulin Resistance, Colon, Anastomosis, Strengthening, Surgical, Enbucrilate

Abstract

Purpose of the study. To investigate the effect of additional strengthening of the colonic anastomosis (CA) using modern adhesive materials on the severity of abdominal contamination in patients with insulin resistance (IR).

Materials and methods. The study involved 80 patients with IR, who underwent surgery with the CA imposition (median age of the patients – 64 (57; 71) years). All patients were divided into 2 groups, depending on the method of strengthening the CA suture: 1 group – 40 patients who underwent the application of a onerow continuous suture (OCS) of the CA (median age of patients – 65 (57; 75) years, 2 group – 40 patients to whom OCS CA was applied, and in order to seal and strengthen the anastomosis zone a modern Nbutylcyanoacrylate tissue adhesive was added (median age of patients – 63,5 (58,5; 70,5) years. The spectrum of microbial flora of secretions from drains near the anastomosis was determined.

Results. The additional use of modern Nbutylcyanoacrylate tissue adhesive to strengthen the area of CA with the imposition of a OCS in patients with IR contributes to a reliable reduction of number of patients with associations consisting of two types of microorganisms compared to the patients without additional strengthening (2 (5,0%) versus 9 (22,5%) of patients, respectively) (χ2 = 5,17, df = 1; р < 0,05), the greater number of patients with no growth of microorganisms in crops from the anastomotic zone ((11 (27,5%) of patients versus 3 (7, 5%) of patients, respectively), as well as fewer cases of high degree of anastomosis zone contamination (3,48 times (χ2 = 7,68, df = 1; р < 0,05)), with prevalence of mild contamination (3, 35 times (χ2 = 15,24, df = 1; р < 0,05)).

Conclusion. The additional use of modern Nbutylcyanoacrylate tissue adhesive to strengthen the area of CA with the imposition of a onerow continuous suture in patients with IR contributes to a reliable reduction of contamination of the area around the anastomosis compared to the patients without additional strengthening.

References

Agadzhanyan DZ. Sposob kompleksnogo lecheniya nesostoyatelnosti nizkogo tolstokishechnogo anastomoza. Sovremennyie naukoemkie tehnologii. 2010; 5: 126–8.

Milyukov VE, Sapin MR, Efimenko NA. Morfofunktsionalnyie osobennosti zazhivleniya kishechnoy ranyi pri formirovanii razlichnyih enteroentero anastomozov. Hirurgiya. 2004; 1: 38–41.

Naumov NV,Runkelov NV,Mahotin DA. Reshenie problemyi nesostoyatelnosti tolstokishechnyih anastomozov pri ruchnom shve. Aktualnyie voprosyi koloproktologii: materialyi konferentsii. Rostov-na-Donu;2001.48–9.

Polyanskiy IYu. Patogenez, lIkuvannya ta profIlaktika nespromozhnostI kishkovih shvIv ta anastomozIv. KlInIchna hIrurgIya. 2005; 11/12: 92–3.

Krasilnikov DM, Nikolaev YaYu, Minnullin MM. Hirurgicheskoe lechenie bolnyih i postradavshih s nesostoyatelnostyu shvov pri zabolevaniyah i travmah organov zheludochno-kishechnogo trakta. Prakticheskaya meditsina. 2013; 2. URL: http://mfvt.ru/category/pmpaper/pm-02-13- hirurgia-onkologia.

Kurbonov KM, Sharipov HYu, Ishanov AA. Sochetannyiy endoskopicheskiy monitoring zazhivleniya tolstokishechnyih anastomozov. Trinadtsatyiy s'ezd Obschestva endoskopicheskih hirurgov Rossii: sb. nauch. tr. Moskva, 2010; 46.

Lohvitskiy CB, Darvin VV. Profilaktika nesostoyatelnosti shvov obodochnoy kishki pri ee povrezhdeniyah. Hirurgiya. 1992; 9–10: S. 51–6.

MItchenko OI, Korpachov VV. DIagnostika I lIkuvannya metabolIchnogo sindromu, tsukrovogo dIabetu, predIabetu I sertsevo-sudinnih zahvoryuvan: metod. rekomendatsIYi RobochoYi grupi z problem metabolIchnogo sindromu, tsukrovogo dIabetu, predIabetu ta sertsevo-sudinnih zahvoryuvan UkraYinskoYi asotsIatsIYi kardIologIv I UkraYinskoYi asotsIatsIYi endokrinologIv. KiYiv, 42 p.

Kuznetsova LV, Babadzhan VD, Harchenko NV, redaktori. ImunologIya. VInnitsya: TOV «MerkyurI PodIllya»;2013. 564 p

Kukleta JF, Freytag C, Weber M. Efficiency and safety of mesh fixation in laparoscopic inguinal hernia repair using n-butyl cyanoacrylate: long-term biocompatibility in over 1,300 mesh fixations. Hernia. 2012; 16: 153–62.

Scognamiglio F, Travan A, Rustighi I. Adhesive and sealant interfaces for general surgery applications. Journal of Biomedical Materials Research. 2016; 104 (3): 626–39.

Romero IL, Malta JB, Silva CB. Antibacterial properties of cyanoacrylate tissue adhesive: Does the polymerization reaction play a role? Indian J Ophthalmol. 2009; 57 (5): 341–4.

Marques BC, Colloni NR, Lopes FG. Comparative study of the healing process of the aponeurosis of the anterior abdominal wall of rats after wound clousure using 3-0 nylon suture and N-butyl-cyanoacrylate tissue adhesive. Acta Cir Bras. 2008; 23 (4): 353–63.

Andres CB, Carlos CV, Jose RM Biocompatibility of n-butyl-cyanoacrylate compared to conventional skin sutures in skin wounds. Revista Odontologica Mexicana. 2013; 17 (2): 81–9.

Published
2021-07-20
How to Cite
Mylytsia, M. M., MylytsiaК. M., Steblianko, V. V., Soldusova, V. V., & Kazakov, V. S. (2021). Effect of additional strengthening of colonic anastomosis on abdominal contamination severity. Modern Medical Technology, (2(49), 50-54. https://doi.org/10.34287/MMT.2(49).2021.9
Section
Original research